Patent snapshot
US 12,729,222 is a utility patent titled “ENHANCED PEPTIDE CONSTRUCTS FOR ALBUMIN BINDING”, invented by Michael Farber.
The application was filed on January 6, 2025 and granted on September 8, 2026, 1 year, 8 months later.
It is one of the patents our firm has obtained in the Chemical area.
Key dates and patent term
| Application filed | January 6, 2025 | |
|---|---|---|
| Patent granted | September 8, 2026 | 1 year, 8 months in prosecution at the U.S. Patent Office |
| Utility term expires (nominal) | January 6, 2045 | 20 years from the earliest U.S. non-provisional filing date. |
The expiration date is calculated from the grant and filing dates on the face of the patent. The actual date may vary based on patent-term adjustment (patent office delay), terminal disclaimer (agreeing to a shorter term), or failing to pay a maintenance fee (due before years 4, 8, and 12). This website is for information purposes only and is not legal advice.
What the classification means
Patent offices file every granted patent under the Cooperative Patent Classification (CPC) scheme. These are the technology areas US 12,729,222 was placed in — a good shortcut to what the invention is considered to be, and to the prior art an examiner would have searched.
- C07K
Peptides (peptides in foodstuffs a23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K…
Bibliographic details
| Patent number | US 12,729,222 |
|---|---|
| Title | ENHANCED PEPTIDE CONSTRUCTS FOR ALBUMIN BINDING |
| Inventors | Michael Farber |
| Filing date | January 6, 2025 |
| Grant date | September 8, 2026 |
| Category | Chemical |
Full text as published by the U.S. Patent Office
The sections below reproduce the official text of US 12,729,222 for reference. Open a section to read it.
Abstract
A synthetic peptide construct comprises an amino acid sequence-RLIEDICLPRWGCLWEDD (SEQ ID NO: 2) (also known as “GLYCLOK”), a flexible, hydrophilic glycine-serine (Gly-Ser) linker, and a polypeptide chain between 25 to 70 amino acids in length, which incorporates an albumin-binding moiety with a dissociation constant (Kd) to albumin of less than 20 nanomolar (nM). This construct may include the sequence RLIEDICLPRWGCLWEDD (SEQ. ID NO: 2) within its terminal 25 amino acids. The albumin-binding moiety may be cyclic, with a disulfide bond formed by at least one cysteine residue. The constructs is used as an agonist to modulate receptor interactions in vivo, enhancing therapeutic efficacy and extending circulating half-life in mammals, including humans. The peptides exhibit significant binding to albumin, enhancing bioavailability and therapeutic duration.
The full text of this recently granted patent is not yet published in machine-readable form. The complete specification is in the PDF above.
US 12,729,222: questions and answers
What is US Patent 12,729,222 about?
US 12,729,222, “ENHANCED PEPTIDE CONSTRUCTS FOR ALBUMIN BINDING”, is a utility patent granted by the United States Patent and Trademark Office on September 8, 2026. In brief: A synthetic peptide construct comprises an amino acid sequence-RLIEDICLPRWGCLWEDD (SEQ ID NO: 2) (also known as “GLYCLOK”), a flexible, hydrophilic glycine-serine (Gly-Ser) linker, and a polypeptide chain between 25 to 70 amino acids in length, which incorporates an albumin-binding moiety with a dis
Who invented US Patent 12,729,222?
The named inventor is Michael Farber.
When was US Patent 12,729,222 filed?
The application was filed on January 6, 2025 and the patent granted on September 8, 2026.
When does US Patent 12,729,222 expire?
The nominal expiration date is January 6, 2045. 20 years from the earliest U.S. non-provisional filing date.
Who was the patent attorney for US Patent 12,729,222?
This patent is in the portfolio of Feigin & Fridman, LLC, patent attorneys in New Jersey. Contact us to discuss protecting your own invention.
Other patents by Michael Farber
- US 12,377,158 — Enhanced peptide constructs for albumin binding
- US 12,357,587 — Cannabinoid monoterpene based pharmaceutical topical composition for musculoskeletal pain
- US 11,903,962 — Isoxazoline complexes and compositions thereof
- US 11,638,714 — Water dissolvable macrocyclic lactone cyclodextrin complexes
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Thinking about a patent of your own?
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